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Article Dans Une Revue Physical Review Letters Année : 2012

Base Pair Openings and Temperature Dependence of DNA Flexibility

Résumé

The relationship of base pair openings to DNA flexibility is examined. Published experimental data on the temperature dependence of the persistence length by two different groups are well described in terms of an inhomogeneous Kratky-Porot model with soft and hard joints, corresponding to open and closed base pairs, and sequence-dependent statistical information about the state of each pair provided by a Peyrard-Bishop-Dauxois (PBD) model calculation with no freely adjustable parameters.
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Dates et versions

ensl-00671264 , version 1 (17-02-2012)

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Nikos Theodorakopoulos, Michel Peyrard. Base Pair Openings and Temperature Dependence of DNA Flexibility. Physical Review Letters, 2012, 108 (7), pp.078104. ⟨10.1103/PhysRevLett.108.078104⟩. ⟨ensl-00671264⟩
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